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Prophylactic cranial irradiation reduces the incidence of brain metastasis in a mouse model of metastatic, HER2-positive breast cancer

Prophylactic cranial irradiation (PCI) can reduce the incidence of brain metastasis and improve overall survival in some patients with acute lymphoblastic leukemia or small-cell lung cancer. We examined the potential effects of PCI in a mouse model of breast cancer brain metastasis. The HER2+ inflam...

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Detalles Bibliográficos
Autores principales: Smith, Daniel L., Debeb, Bisrat G., Diagaradjane, Parmeswaran, Larson, Richard, Kumar, Swaminathan, Ning, Jing, Lacerda, Lara, Li, Li, Woodward, Wendy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8045965/
https://www.ncbi.nlm.nih.gov/pubmed/33884104
http://dx.doi.org/10.18632/genesandcancer.212