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Characterization of Primary Cilia in Osteoblasts Isolated From Patients With ADPKD and CKD

Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited cause of chronic kidney disease (CKD) and leads to a specific type of bone disease. The primary cilium is a major cellular organelle implicated in the pathophysiology of ADPKD caused by mutations in polycystin‐1 (PKD1)...

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Detalles Bibliográficos
Autores principales: Pereira, Renata C, Gitomer, Berenice Y, Chonchol, Michel, Harris, Peter C, Noche, Kathleen J, Salusky, Isidro B, Albrecht, Lauren V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8046038/
https://www.ncbi.nlm.nih.gov/pubmed/33869988
http://dx.doi.org/10.1002/jbm4.10464