A Bisphosphonate With a Low Hydroxyapatite Binding Affinity Prevents Bone Loss in Mice After Ovariectomy and Reverses Rapidly With Treatment Cessation

Bisphosphonates (BPs) are a mainstay of osteoporosis treatment; however, concerns about bone health based on oversuppression of remodeling remain. Long‐term bone remodeling suppression adversely affects bone material properties with microdamage accumulation and reduced fracture toughness in animals...

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Detalles Bibliográficos
Autores principales: Coffman, Abigail A, Basta‐Pljakic, Jelena, Guerra, Rosa M, Ebetino, Frank H, Lundy, Mark W, Majeska, Robert J, Schaffler, Mitchell B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8046044/
https://www.ncbi.nlm.nih.gov/pubmed/33869992
http://dx.doi.org/10.1002/jbm4.10476

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8046044/
https://www.ncbi.nlm.nih.gov/pubmed/33869992
http://dx.doi.org/10.1002/jbm4.10476

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