Enhanced differentiation of human induced pluripotent stem cells toward the midbrain dopaminergic neuron lineage through GLYPICAN‐4 downregulation

Enhancing the differentiation potential of human induced pluripotent stem cells (hiPSC) into disease‐relevant cell types is instrumental for their widespread application in medicine. Here, we show that hiPSCs downregulated for the signaling modulator GLYPICAN‐4 (GPC4) acquire a new biological state...

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Detalles Bibliográficos
Autores principales: Corti, Serena, Bonjean, Remi, Legier, Thomas, Rattier, Diane, Melon, Christophe, Salin, Pascal, Toso, Erik A., Kyba, Michael, Kerkerian‐Le Goff, Lydia, Maina, Flavio, Dono, Rosanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Pluripotent Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8046045/
https://www.ncbi.nlm.nih.gov/pubmed/33528918
http://dx.doi.org/10.1002/sctm.20-0177

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8046045/
https://www.ncbi.nlm.nih.gov/pubmed/33528918
http://dx.doi.org/10.1002/sctm.20-0177

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