Evaluation of the antiproliferative effects of the HASPIN inhibitor CHR-6494 in breast cancer cell lines

HASPIN is a serine/threonine kinase that regulates mitosis by phosphorylating histone H3 at threonine 3. The expression levels of HASPIN in various cancers are associated with tumor malignancy and poor survival, suggesting that HASPIN inhibition may suppress cancer growth. As HASPIN mRNA levels are...

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Detalles Bibliográficos
Autores principales: Nishida-Fukuda, Hisayo, Tokuhiro, Keizo, Ando, Yukio, Matsushita, Hiroaki, Wada, Morimasa, Tanaka, Hiromitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8046223/
https://www.ncbi.nlm.nih.gov/pubmed/33852630
http://dx.doi.org/10.1371/journal.pone.0249912

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8046223/
https://www.ncbi.nlm.nih.gov/pubmed/33852630
http://dx.doi.org/10.1371/journal.pone.0249912

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