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miRGTF-net: Integrative miRNA-gene-TF network analysis reveals key drivers of breast cancer recurrence

Analysis of regulatory networks is a powerful framework for identification and quantification of intracellular interactions. We introduce miRGTF-net, a novel tool for construction of miRNA-gene-TF networks. We consider multiple transcriptional and post-transcriptional interaction types, including re...

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Detalles Bibliográficos
Autores principales: Nersisyan, Stepan, Galatenko, Alexei, Galatenko, Vladimir, Shkurnikov, Maxim, Tonevitsky, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8046230/
https://www.ncbi.nlm.nih.gov/pubmed/33852600
http://dx.doi.org/10.1371/journal.pone.0249424