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A nonviral, nonintegrating DNA nanovector platform for the safe, rapid, and persistent manufacture of recombinant T cells

The compelling need to provide adoptive cell therapy (ACT) to an increasing number of oncology patients within a meaningful therapeutic window makes the development of an efficient, fast, versatile, and safe genetic tool for creating recombinant T cells indispensable. In this study, we used noninteg...

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Detalles Bibliográficos
Autores principales: Bozza, Matthias, De Roia, Alice, Correia, Margareta P., Berger, Aileen, Tuch, Alexandra, Schmidt, Andreas, Zörnig, Inka, Jäger, Dirk, Schmidt, Patrick, Harbottle, Richard P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8046366/
https://www.ncbi.nlm.nih.gov/pubmed/33853779
http://dx.doi.org/10.1126/sciadv.abf1333