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Chemical conversion of human epidermal stem cells into intestinal goblet cells for modeling mucus-microbe interaction and therapy

Intestinal goblet cells secrete mucus layers protecting the intestinal epithelia against injuries. It is challenging to study the interaction of goblet cells, mucus layers, and gut microbiota because of difficulty in producing goblet cells and mucus models. We generate intestinal goblet cells from h...

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Detalles Bibliográficos
Autores principales: Zhao, Andong, Qin, Hua, Sun, Mengli, Tang, Mao, Mei, Jinyu, Ma, Kui, Fu, Xiaobing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8046373/
https://www.ncbi.nlm.nih.gov/pubmed/33853767
http://dx.doi.org/10.1126/sciadv.abb2213