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Mitochondrial Aurora kinase A induces mitophagy by interacting with MAP1LC3 and Prohibitin 2

Epithelial and haematologic tumours often show the overexpression of the serine/threonine kinase AURKA. Recently, AURKA was shown to localise at mitochondria, where it regulates mitochondrial dynamics and ATP production. Here we define the molecular mechanisms of AURKA in regulating mitochondrial tu...

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Detalles Bibliográficos
Autores principales: Bertolin, Giulia, Alves-Guerra, Marie-Clotilde, Cheron, Angélique, Burel, Agnès, Prigent, Claude, Le Borgne, Roland, Tramier, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8046421/
https://www.ncbi.nlm.nih.gov/pubmed/33820826
http://dx.doi.org/10.26508/lsa.202000806