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Mitochondrial Aurora kinase A induces mitophagy by interacting with MAP1LC3 and Prohibitin 2
Epithelial and haematologic tumours often show the overexpression of the serine/threonine kinase AURKA. Recently, AURKA was shown to localise at mitochondria, where it regulates mitochondrial dynamics and ATP production. Here we define the molecular mechanisms of AURKA in regulating mitochondrial tu...
Autores principales: | Bertolin, Giulia, Alves-Guerra, Marie-Clotilde, Cheron, Angélique, Burel, Agnès, Prigent, Claude, Le Borgne, Roland, Tramier, Marc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8046421/ https://www.ncbi.nlm.nih.gov/pubmed/33820826 http://dx.doi.org/10.26508/lsa.202000806 |
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