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Edoxaban Dosing Time Affects Blood Coagulation Inhibition in Rats

Coagulation–fibrinolytic system activity shows daily rhythmicity, with hypercoagulability in the morning and hypocoagulability in the evening. Consequently, the efficacy of anticoagulants may be influenced by their dosing time. Edoxaban, a selective inhibitor of the active form of coagulation factor...

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Detalles Bibliográficos
Autores principales: Nagata, Naoto, Kawasumi, Muneo, Fujimura, Akio, Ando, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Georg Thieme Verlag KG 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8046513/
https://www.ncbi.nlm.nih.gov/pubmed/33870074
http://dx.doi.org/10.1055/s-0041-1725041