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Structural basis of nucleosome transcription mediated by Chd1 and FACT

Efficient transcription of RNA polymerase II (Pol II) through nucleosomes requires the help of various factors. Here we show biochemically that Pol II transcription through a nucleosome is facilitated by the chromatin remodeler Chd1 and the histone chaperone FACT when the elongation factors Spt4/5 a...

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Detalles Bibliográficos
Autores principales: Farnung, Lucas, Ochmann, Moritz, Engeholm, Maik, Cramer, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8046669/
https://www.ncbi.nlm.nih.gov/pubmed/33846633
http://dx.doi.org/10.1038/s41594-021-00578-6