Mint3 depletion-mediated glycolytic and oxidative alterations promote pyroptosis and prevent the spread of Listeria monocytogenes infection in macrophages

Listeria monocytogenes (LM) infection induces pyroptosis, a form of regulated necrosis, in host macrophages via inflammasome activation. Here, we examined the role of Mint3 in macrophages, which promotes glycolysis via hypoxia-inducible factor-1 activation, during the initiation of pyroptosis follow...

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Detalles Bibliográficos
Autores principales: Uematsu, Takayuki, Tsuchiya, Kohsuke, Kobayashi, Noritada, Seiki, Motoharu, Inoue, Jun-ichiro, Kaneko, Shuichi, Sakamoto, Takeharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8046764/
https://www.ncbi.nlm.nih.gov/pubmed/33854054
http://dx.doi.org/10.1038/s41419-021-03691-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8046764/
https://www.ncbi.nlm.nih.gov/pubmed/33854054
http://dx.doi.org/10.1038/s41419-021-03691-y

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