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Regulator of G protein signaling 17 represents a novel target for treating cisplatin induced hearing loss

Regulators of G protein signaling (RGS) accelerate the GTPase activity of G proteins to enable rapid termination of the signals triggered by G protein-coupled receptors (GPCRs). Activation of several GPCRs, including cannabinoid receptor 2 (CB2R) and adenosine A(1) receptor (A(1)AR), protects agains...

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Detalles Bibliográficos
Autores principales: Dhukhwa, Asmita, Al Aameri, Raheem F. H., Sheth, Sandeep, Mukherjea, Debashree, Rybak, Leonard, Ramkumar, Vickram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8046767/
https://www.ncbi.nlm.nih.gov/pubmed/33854102
http://dx.doi.org/10.1038/s41598-021-87387-5