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Synthesis of no-carrier-added [(188, 189, 191)Pt]cisplatin from a cyclotron produced (188, 189, 191)PtCl(4)(2−) complex

We developed a novel method for production of no-carrier-added (n.c.a.) [(188, 189, 191)Pt]Pt(II)Cl(4)(2−) from an Ir target material, and then synthesized n.c.a. [*Pt]cis-[Pt(II)Cl(2)(NH(3))(2)] ([*Pt]cisplatin) from [*Pt]Pt(II)Cl(4)(2−). [*Pt]Pt(II)Cl(4)(2−) was prepared as a synthetic precursor o...

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Detalles Bibliográficos
Autores principales: Obata, Honoka, Minegishi, Katsuyuki, Nagatsu, Kotaro, Ogawa, Mikako, Zhang, Ming-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8046966/
https://www.ncbi.nlm.nih.gov/pubmed/33854142
http://dx.doi.org/10.1038/s41598-021-87576-2