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Identification and functional analysis of a biflavone as a novel inhibitor of transient receptor potential vanilloid 4-dependent atherogenic processes

Atherosclerosis, a chronic inflammatory disease of large arteries, is the major contributor to the growing burden of cardiovascular disease-related mortality and morbidity. During early atherogenesis, as a result of inflammation and endothelial dysfunction, monocytes transmigrate into the aortic int...

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Detalles Bibliográficos
Autores principales: Alharbi, Mazen O., Dutta, Bidisha, Goswami, Rishov, Sharma, Shweta, Lei, Kai Y., Rahaman, Shaik O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047007/
https://www.ncbi.nlm.nih.gov/pubmed/33854174
http://dx.doi.org/10.1038/s41598-021-87696-9