Spine impairment in mice high-expressing neuregulin 1 due to LIMK1 activation

The genes encoding for neuregulin1 (NRG1), a growth factor, and its receptor ErbB4 are both risk factors of major depression disorder and schizophrenia (SZ). They have been implicated in neural development and synaptic plasticity. However, exactly how NRG1 variations lead to SZ remains unclear. Inde...

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Detalles Bibliográficos
Autores principales: Chen, Peng, Jing, Hongyang, Xiong, Mingtao, Zhang, Qian, Lin, Dong, Ren, Dongyan, Wang, Shunqi, Yin, Dongmin, Chen, Yongjun, Zhou, Tian, Li, Baoming, Fei, Erkang, Pan, Bing-Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047019/
https://www.ncbi.nlm.nih.gov/pubmed/33854034
http://dx.doi.org/10.1038/s41419-021-03687-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047019/
https://www.ncbi.nlm.nih.gov/pubmed/33854034
http://dx.doi.org/10.1038/s41419-021-03687-8

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