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Spine impairment in mice high-expressing neuregulin 1 due to LIMK1 activation
The genes encoding for neuregulin1 (NRG1), a growth factor, and its receptor ErbB4 are both risk factors of major depression disorder and schizophrenia (SZ). They have been implicated in neural development and synaptic plasticity. However, exactly how NRG1 variations lead to SZ remains unclear. Inde...
Autores principales: | Chen, Peng, Jing, Hongyang, Xiong, Mingtao, Zhang, Qian, Lin, Dong, Ren, Dongyan, Wang, Shunqi, Yin, Dongmin, Chen, Yongjun, Zhou, Tian, Li, Baoming, Fei, Erkang, Pan, Bing-Xing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047019/ https://www.ncbi.nlm.nih.gov/pubmed/33854034 http://dx.doi.org/10.1038/s41419-021-03687-8 |
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