Nuclear ErbB2 represses DEPTOR transcription to inhibit autophagy in breast cancer cells

ErbB2, a classical receptor tyrosine kinase, is frequently overexpressed in breast cancer cells. Although the role of ErbB2 in the transmission of extracellular signals to intracellular matrix has been widely studied, the functions of nuclear ErbB2 remain largely elusive. Here, we report a novel fun...

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Detalles Bibliográficos
Autores principales: Bi, Yanli, Gong, Longyuan, Liu, Pengyuan, Xiong, Xiufang, Zhao, Yongchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047043/
https://www.ncbi.nlm.nih.gov/pubmed/33854045
http://dx.doi.org/10.1038/s41419-021-03686-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047043/
https://www.ncbi.nlm.nih.gov/pubmed/33854045
http://dx.doi.org/10.1038/s41419-021-03686-9

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