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Nuclear ErbB2 represses DEPTOR transcription to inhibit autophagy in breast cancer cells
ErbB2, a classical receptor tyrosine kinase, is frequently overexpressed in breast cancer cells. Although the role of ErbB2 in the transmission of extracellular signals to intracellular matrix has been widely studied, the functions of nuclear ErbB2 remain largely elusive. Here, we report a novel fun...
Autores principales: | Bi, Yanli, Gong, Longyuan, Liu, Pengyuan, Xiong, Xiufang, Zhao, Yongchao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047043/ https://www.ncbi.nlm.nih.gov/pubmed/33854045 http://dx.doi.org/10.1038/s41419-021-03686-9 |
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