High-throughput kinase inhibitor screening reveals roles for Aurora and Nuak kinases in neurite initiation and dendritic branching

Kinases are essential regulators of a variety of cellular signaling processes, including neurite formation—a foundational step in neurodevelopment. Aberrant axonal sprouting and failed regeneration of injured axons are associated with conditions like traumatic injury, neurodegenerative disease, and...

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Detalles Bibliográficos
Autores principales: Blazejewski, Sara M., Bennison, Sarah A., Liu, Xiaonan, Toyo-oka, Kazuhito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047044/
https://www.ncbi.nlm.nih.gov/pubmed/33854138
http://dx.doi.org/10.1038/s41598-021-87521-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047044/
https://www.ncbi.nlm.nih.gov/pubmed/33854138
http://dx.doi.org/10.1038/s41598-021-87521-3

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