Camptothecin Regulates Microglia Polarization and Exerts Neuroprotective Effects via Activating AKT/Nrf2/HO-1 and Inhibiting NF-κB Pathways In Vivo and In Vitro

Microglia, the main immune cells in the brain, participate in the innate immune response in the central nervous system (CNS). Studies have shown that microglia can be polarized into pro-inflammatory M1 and anti-inflammatory M2 phenotypes. Accumulated evidence suggests that over-activated M1 microgli...

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Detalles Bibliográficos
Autores principales: He, Dewei, Fu, Shoupeng, Zhou, Ang, Su, Yingchun, Gao, Xiyu, Zhang, Yufei, Huang, Bingxu, Du, Jian, Liu, Dianfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047064/
https://www.ncbi.nlm.nih.gov/pubmed/33868235
http://dx.doi.org/10.3389/fimmu.2021.619761

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047064/
https://www.ncbi.nlm.nih.gov/pubmed/33868235
http://dx.doi.org/10.3389/fimmu.2021.619761

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