Engineering Cofactor Specificity of a Thermostable Phosphite Dehydrogenase for a Highly Efficient and Robust NADPH Regeneration System

Nicotinamide adenine dinucleotide phosphate (NADP)-dependent dehydrogenases catalyze a range of chemical reactions useful for practical applications. However, their dependence on the costly cofactor, NAD(P)H remains a challenge which must be addressed. Here, we engineered a thermotolerant phosphite...

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Detalles Bibliográficos
Autores principales: Abdel-Hady, Gamal Nasser, Ikeda, Takeshi, Ishida, Takenori, Funabashi, Hisakage, Kuroda, Akio, Hirota, Ryuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047080/
https://www.ncbi.nlm.nih.gov/pubmed/33869158
http://dx.doi.org/10.3389/fbioe.2021.647176

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047080/
https://www.ncbi.nlm.nih.gov/pubmed/33869158
http://dx.doi.org/10.3389/fbioe.2021.647176

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