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The Role of Mitochondrial Dysfunction and ER Stress in TDP-43 and C9ORF72 ALS
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease of the motor system with complex determinants, including genetic and non-genetic factors. Despite this heterogeneity, a key pathological signature is the mislocalization and aggregation of specific proteins in the cytoplasm, suggesti...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047135/ https://www.ncbi.nlm.nih.gov/pubmed/33867942 http://dx.doi.org/10.3389/fncel.2021.653688 |