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The Role of Mitochondrial Dysfunction and ER Stress in TDP-43 and C9ORF72 ALS

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease of the motor system with complex determinants, including genetic and non-genetic factors. Despite this heterogeneity, a key pathological signature is the mislocalization and aggregation of specific proteins in the cytoplasm, suggesti...

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Detalles Bibliográficos
Autores principales:	Dafinca, Ruxandra, Barbagallo, Paola, Talbot, Kevin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cellular Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047135/ https://www.ncbi.nlm.nih.gov/pubmed/33867942 http://dx.doi.org/10.3389/fncel.2021.653688

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