Overexpression of SERCA2a Alleviates Cardiac Microvascular Ischemic Injury by Suppressing Mfn2-Mediated ER/Mitochondrial Calcium Tethering

Our previous research has shown that type-2a Sarco/endoplasmic reticulum Ca(2+)-ATPase (SERCA2a) undergoes posttranscriptional oxidative modifications in cardiac microvascular endothelial cells (CMECs) in the context of excessive cardiac oxidative injury. However, whether SERCA2a inactivity induces...

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Detalles Bibliográficos
Autores principales: Tian, Feng, Zhang, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047138/
https://www.ncbi.nlm.nih.gov/pubmed/33869181
http://dx.doi.org/10.3389/fcell.2021.636553

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047138/
https://www.ncbi.nlm.nih.gov/pubmed/33869181
http://dx.doi.org/10.3389/fcell.2021.636553

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