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Bilirubin Induces Pain Desensitization in Cholestasis by Activating 5-Hydroxytryptamine 3A Receptor in Spinal Cord
BACKGROUND: Cholestasis patients often suffer from pain desensitization, resulting in serious complications in perioperative period. This study was aim to investigate the mechanism of bilirubin in cholestasis mediating pain desensitization through 5-hydroxytryptamine 3A (5-HT(3A)) receptor activatio...
Autores principales: | Kong, Erliang, Wang, Hongqian, Wang, Xiaoqiang, Zhang, Yan, Zhang, Jinmin, Yu, Weifeng, Feng, Xudong, Sun, Yuming, Wu, Feixiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047141/ https://www.ncbi.nlm.nih.gov/pubmed/33869168 http://dx.doi.org/10.3389/fcell.2021.605855 |
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