A Highly Conserved Shh Enhancer Coordinates Hypothalamic and Craniofacial Development

Enhancers that are conserved deep in evolutionary time regulate characteristics held in common across taxonomic classes. Here, deletion of the highly conserved Shh enhancer SBE2 (Shh brain enhancer 2) in mouse markedly reduced Shh expression within the embryonic brain specifically in the rostral die...

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Detalles Bibliográficos
Autores principales: Crane-Smith, Zoe, Schoenebeck, Jeffrey, Graham, Katy A., Devenney, Paul S., Rose, Lorraine, Ditzell, Mark, Anderson, Eve, Thomson, Joseph I., Klenin, Natasha, Kurrasch, Deborah M., Lettice, Laura A., Hill, Robert E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047142/
https://www.ncbi.nlm.nih.gov/pubmed/33869166
http://dx.doi.org/10.3389/fcell.2021.595744

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047142/
https://www.ncbi.nlm.nih.gov/pubmed/33869166
http://dx.doi.org/10.3389/fcell.2021.595744

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