SSSPTA is essential for serine palmitoyltransferase function during development and hematopoiesis

Serine palmitoyltransferase complex (SPT) mediates the first and rate-limiting step in the de novo sphingolipid biosynthetic pathway. The larger subunits SPTLC1 and SPTLC2/SPTLC3 together form the catalytic core while a smaller third subunit either SSSPTA or SSSPTB has been shown to increase the cat...

Descripción completa

Detalles Bibliográficos
Autores principales: Parthibane, Velayoudame, Lin, Jing, Acharya, Diwash, Abimannan, Thiruvaimozhi, Srideshikan, Sargur Madabushi, Klarmann, Kimberly, Yang, Acong, Soheilian, Ferri, Nagashima, Kunio, Fox, Stephen D., Andresson, Thorkell, Tessarollo, Lino, Keller, Jonathan R., Acharya, Usha, Acharya, Jairaj K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047174/
https://www.ncbi.nlm.nih.gov/pubmed/33662400
http://dx.doi.org/10.1016/j.jbc.2021.100491

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047174/
https://www.ncbi.nlm.nih.gov/pubmed/33662400
http://dx.doi.org/10.1016/j.jbc.2021.100491

Ejemplares similares