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Association Between Variants in Calcineurin Inhibitor Pharmacokinetic and Pharmacodynamic Genes and Renal Dysfunction in Adult Heart Transplant Recipients

Background: The goal of the study was to assess the relationship between single nucleotide variants (SNVs) in calcineurin inhibitor (CNI) pharmacokinetic and pharmacodynamic genes and renal dysfunction in adult heart transplant (HTx) recipients. Methods: This retrospective analysis included N = 192...

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Detalles Bibliográficos
Autores principales: Oreschak, Kris, Saba, Laura M., Rafaels, Nicholas, Ambardekar, Amrut V., Deininger, Kimberly M., Page, Robert L., Lindenfeld, JoAnn, Aquilante, Christina L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047196/
https://www.ncbi.nlm.nih.gov/pubmed/33868389
http://dx.doi.org/10.3389/fgene.2021.658983