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HIV Neuroinflammation: The Role of Exosomes in Cell Signaling, Prognostic and Diagnostic Biomarkers and Drug Delivery

Fifty to sixty percent of HIV-1 positive patients experience HIV-1 associated neurocognitive disorders (HAND) likely due to persistent inflammation and blood–brain barrier (BBB) dysfunction. The role that microglia and astrocytes play in HAND pathogenesis has been well delineated; however, the role...

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Detalles Bibliográficos
Autores principales: Mahajan, Supriya D., Ordain, Nigel Smith, Kutscher, Hilliard, Karki, Shanta, Reynolds, Jessica L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047197/
https://www.ncbi.nlm.nih.gov/pubmed/33869183
http://dx.doi.org/10.3389/fcell.2021.637192