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Advances in the Role of Leucine-Sensing in the Regulation of Protein Synthesis in Aging Skeletal Muscle

Skeletal muscle anabolic resistance (i.e., the decrease in muscle protein synthesis (MPS) in response to anabolic stimuli such as amino acids and exercise) has been identified as a major cause of age-related sarcopenia, to which blunted nutrition-sensing contributes. In recent years, it has been sug...

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Detalles Bibliográficos
Autores principales: Zhao, Yan, Cholewa, Jason, Shang, Huayu, Yang, Yueqin, Ding, Xiaomin, Wang, Qianjin, Su, Quansheng, Zanchi, Nelo Eidy, Xia, Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047301/
https://www.ncbi.nlm.nih.gov/pubmed/33869199
http://dx.doi.org/10.3389/fcell.2021.646482