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Revisiting the Coreceptor Function of Complement Receptor Type 2 (CR2, CD21); Coengagement With the B-Cell Receptor Inhibits the Activation, Proliferation, and Antibody Production of Human B Cells

The positive coreceptor function of complement receptor type 2 [CR2 (CD21)] on B cells is generally accepted, although its role in the enhancement of antibody production had only been proven in mice. The importance of this phenomenon prompted reinvestigation of the functional consequences of coclust...

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Detalles Bibliográficos
Autores principales: Kovács, Kristóf G., Mácsik-Valent, Bernadett, Matkó, János, Bajtay, Zsuzsa, Erdei, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047317/
https://www.ncbi.nlm.nih.gov/pubmed/33868238
http://dx.doi.org/10.3389/fimmu.2021.620427