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PIF1 helicase promotes break‐induced replication in mammalian cells

Break‐induced replication (BIR) is a specialized homologous‐recombination pathway for DNA double‐strand break (DSB) repair, which often induces genome instability. In this study, we establish EGFP‐based recombination reporters to systematically study BIR in mammalian cells and demonstrate an importa...

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Detalles Bibliográficos
Autores principales: Li, Shibo, Wang, Hailong, Jehi, Sanaa, Li, Jun, Liu, Shuo, Wang, Zi, Truong, Lan, Chiba, Takuya, Wang, Zefeng, Wu, Xiaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047440/
https://www.ncbi.nlm.nih.gov/pubmed/33470420
http://dx.doi.org/10.15252/embj.2020104509