Mitochondrial translation deficiency impairs NAD(+)‐mediated lysosomal acidification

Mitochondrial translation dysfunction is associated with neurodegenerative and cardiovascular diseases. Cells eliminate defective mitochondria by the lysosomal machinery via autophagy. The relationship between mitochondrial translation and lysosomal function is unknown. In this study, mitochondrial...

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Detalles Bibliográficos
Autores principales: Yagi, Mikako, Toshima, Takahiro, Amamoto, Rie, Do, Yura, Hirai, Haruka, Setoyama, Daiki, Kang, Dongchon, Uchiumi, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047443/
https://www.ncbi.nlm.nih.gov/pubmed/33528041
http://dx.doi.org/10.15252/embj.2020105268

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047443/
https://www.ncbi.nlm.nih.gov/pubmed/33528041
http://dx.doi.org/10.15252/embj.2020105268

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