Genetic and epigenetic regulation of the non-muscle myosin light chain kinase isoform by lung inflammatory factors and mechanical stress

Rationale: The myosin light chain kinase gene, MYLK, encodes three proteins via unique promoters, including the non-muscle isoform of myosin light chain kinase (nmMLCK), a cytoskeletal protein centrally involved in regulation of vascular integrity. As MYLK coding SNPs are associated with severe infl...

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Detalles Bibliográficos
Autores principales: Sun, Xiaoguang, Sun, Belinda L., Sammani, Saad, Bermudez, Tadeo, Dudek, Steven M., Camp, Sara M., Garcia, Joe G.N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2021
Materias:
Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047480/
https://www.ncbi.nlm.nih.gov/pubmed/33792658
http://dx.doi.org/10.1042/CS20201448

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047480/
https://www.ncbi.nlm.nih.gov/pubmed/33792658
http://dx.doi.org/10.1042/CS20201448

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