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Genetic and epigenetic regulation of the non-muscle myosin light chain kinase isoform by lung inflammatory factors and mechanical stress
Rationale: The myosin light chain kinase gene, MYLK, encodes three proteins via unique promoters, including the non-muscle isoform of myosin light chain kinase (nmMLCK), a cytoskeletal protein centrally involved in regulation of vascular integrity. As MYLK coding SNPs are associated with severe infl...
Autores principales: | Sun, Xiaoguang, Sun, Belinda L., Sammani, Saad, Bermudez, Tadeo, Dudek, Steven M., Camp, Sara M., Garcia, Joe G.N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047480/ https://www.ncbi.nlm.nih.gov/pubmed/33792658 http://dx.doi.org/10.1042/CS20201448 |
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