A COVID moonshot: assessment of ligand binding to the SARS-CoV-2 main protease by saturation transfer difference NMR spectroscopy

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the etiological cause of the coronavirus disease 2019, for which no effective antiviral therapeutics are available. The SARS-CoV-2 main protease (M(pro)) is essential for viral replication and constitutes a promising therapeutic target....

Descripción completa

Detalles Bibliográficos
Autores principales: Kantsadi, Anastassia L., Cattermole, Emma, Matsoukas, Minos-Timotheos, Spyroulias, Georgios A., Vakonakis, Ioannis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047523/
https://www.ncbi.nlm.nih.gov/pubmed/33856612
http://dx.doi.org/10.1007/s10858-021-00365-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047523/
https://www.ncbi.nlm.nih.gov/pubmed/33856612
http://dx.doi.org/10.1007/s10858-021-00365-x

Ejemplares similares