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A COVID moonshot: assessment of ligand binding to the SARS-CoV-2 main protease by saturation transfer difference NMR spectroscopy

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the etiological cause of the coronavirus disease 2019, for which no effective antiviral therapeutics are available. The SARS-CoV-2 main protease (M(pro)) is essential for viral replication and constitutes a promising therapeutic target....

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Detalles Bibliográficos
Autores principales:	Kantsadi, Anastassia L., Cattermole, Emma, Matsoukas, Minos-Timotheos, Spyroulias, Georgios A., Vakonakis, Ioannis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Netherlands 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047523/ https://www.ncbi.nlm.nih.gov/pubmed/33856612 http://dx.doi.org/10.1007/s10858-021-00365-x

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