Lipotoxic hepatocyte-derived exosomal miR-1297 promotes hepatic stellate cell activation through the PTEN signaling pathway in metabolic-associated fatty liver disease

BACKGROUND: Exosomes play an important role in metabolic-associated fatty liver disease (MAFLD), but the mechanism by which exosomes participate in MAFLD still remain unclear. AIM: To figure out the function of lipotoxic exosomal miR-1297 in MAFLD. METHODS: MicroRNA sequencing was used to detect dif...

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Detalles Bibliográficos
Autores principales: Luo, Xin, Luo, Sheng-Zheng, Xu, Zi-Xin, Zhou, Cui, Li, Zheng-Hong, Zhou, Xiao-Yan, Xu, Ming-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2021
Materias:
Basic Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047533/
https://www.ncbi.nlm.nih.gov/pubmed/33911465
http://dx.doi.org/10.3748/wjg.v27.i14.1419

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047533/
https://www.ncbi.nlm.nih.gov/pubmed/33911465
http://dx.doi.org/10.3748/wjg.v27.i14.1419

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