Radiosensitization in Pediatric High-Grade Glioma: Targets, Resistance and Developments

Pediatric high-grade gliomas (pHGG) are the leading cause of cancer-related death in children. These epigenetically dysregulated tumors often harbor mutations in genes encoding histone 3, which contributes to a stem cell-like, therapy-resistant phenotype. Furthermore, pHGG are characterized by a dif...

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Detalles Bibliográficos
Autores principales: Metselaar, Dennis S., du Chatinier, Aimée, Stuiver, Iris, Kaspers, Gertjan J. L., Hulleman, Esther
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047603/
https://www.ncbi.nlm.nih.gov/pubmed/33869066
http://dx.doi.org/10.3389/fonc.2021.662209

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047603/
https://www.ncbi.nlm.nih.gov/pubmed/33869066
http://dx.doi.org/10.3389/fonc.2021.662209

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