Identification of Bioactive SNM1A Inhibitors

[Image: see text] SNM1A is a nuclease required to repair DNA interstrand cross-links (ICLs) caused by some anticancer compounds, including cisplatin. Unlike other nucleases involved in ICL repair, SNM1A is not needed to restore other forms of DNA damage. As such, SNM1A is an attractive target for se...

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Detalles Bibliográficos
Autores principales: Buzon, Beverlee, Grainger, Ryan A., Rzadki, Cameron, Huang, Simon York Ming, Junop, Murray
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047731/
https://www.ncbi.nlm.nih.gov/pubmed/33869915
http://dx.doi.org/10.1021/acsomega.0c03528

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047731/
https://www.ncbi.nlm.nih.gov/pubmed/33869915
http://dx.doi.org/10.1021/acsomega.0c03528

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