Reconstruction of ARNT PAS-B Unfolding Pathways by Steered Molecular Dynamics and Artificial Neural Networks

[Image: see text] Several experimental studies indicated that large conformational changes, including partial domain unfolding, have a role in the functional mechanisms of the basic helix loop helix Per/ARNT/SIM (bHLH-PAS) transcription factors. Recently, single-molecule atomic force microscopy (AFM...

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Detalles Bibliográficos
Autores principales: Motta, Stefano, Pandini, Alessandro, Fornili, Arianna, Bonati, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047803/
https://www.ncbi.nlm.nih.gov/pubmed/33780250
http://dx.doi.org/10.1021/acs.jctc.0c01308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047803/
https://www.ncbi.nlm.nih.gov/pubmed/33780250
http://dx.doi.org/10.1021/acs.jctc.0c01308

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