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Reconstruction of ARNT PAS-B Unfolding Pathways by Steered Molecular Dynamics and Artificial Neural Networks

[Image: see text] Several experimental studies indicated that large conformational changes, including partial domain unfolding, have a role in the functional mechanisms of the basic helix loop helix Per/ARNT/SIM (bHLH-PAS) transcription factors. Recently, single-molecule atomic force microscopy (AFM...

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Detalles Bibliográficos
Autores principales:	Motta, Stefano, Pandini, Alessandro, Fornili, Arianna, Bonati, Laura
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2021
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047803/ https://www.ncbi.nlm.nih.gov/pubmed/33780250 http://dx.doi.org/10.1021/acs.jctc.0c01308

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