An antibiotic-resistance conferring mutation in a neisserial porin: Structure, ion flux, and ampicillin binding

Gram-negative bacteria cause the majority of highly drug-resistant bacterial infections. To cross the outer membrane of the complex Gram-negative cell envelope, antibiotics permeate through porins, trimeric channel proteins that enable the exchange of small polar molecules. Mutations in porins contr...

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Detalles Bibliográficos
Autores principales: Bartsch, Annika, Ives, Callum M., Kattner, Christof, Pein, Florian, Diehn, Manuel, Tanabe, Mikio, Munk, Axel, Zachariae, Ulrich, Steinem, Claudia, Llabrés, Salomé
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047873/
https://www.ncbi.nlm.nih.gov/pubmed/33675718
http://dx.doi.org/10.1016/j.bbamem.2021.183601

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047873/
https://www.ncbi.nlm.nih.gov/pubmed/33675718
http://dx.doi.org/10.1016/j.bbamem.2021.183601

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