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An antibiotic-resistance conferring mutation in a neisserial porin: Structure, ion flux, and ampicillin binding
Gram-negative bacteria cause the majority of highly drug-resistant bacterial infections. To cross the outer membrane of the complex Gram-negative cell envelope, antibiotics permeate through porins, trimeric channel proteins that enable the exchange of small polar molecules. Mutations in porins contr...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047873/ https://www.ncbi.nlm.nih.gov/pubmed/33675718 http://dx.doi.org/10.1016/j.bbamem.2021.183601 |