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microRNA strand selection: Unwinding the rules

microRNAs (miRNAs) play a central role in the regulation of gene expression by targeting specific mRNAs for degradation or translational repression. Each miRNA is post‐transcriptionally processed into a duplex comprising two strands. One of the two miRNA strands is selectively loaded into an Argonau...

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Detalles Bibliográficos
Autores principales: Medley, Jeffrey C., Panzade, Ganesh, Zinovyeva, Anna Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047885/
https://www.ncbi.nlm.nih.gov/pubmed/32954644
http://dx.doi.org/10.1002/wrna.1627