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Lentivirus vector-mediated genetic manipulation of oncogenic pathways induces tumor formation in rabbit brain

Translation of promising experimental therapies from rodent models to clinical success has been complicated as the novel therapies often fail in clinical trials. Existing rodent glioma models generally do not allow for preclinical evaluation of the efficiency of novel therapies in combination with s...

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Detalles Bibliográficos
Autores principales: Ahmad, Farizan, Hyvärinen, Anna, Pirinen, Agnieszka, Olsson, Venla, Rummukainen, Jaana, Immonen, Arto, Närväinen, Johanna, Tuunanen, Pasi, Liimatainen, Timo, Kärkkäinen, Virve, Koistinaho, Jari, Ylä-Herttuala, Seppo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047887/
https://www.ncbi.nlm.nih.gov/pubmed/33846766
http://dx.doi.org/10.3892/mmr.2021.12061