The antidiabetic drug troglitazone protects against PrP (106–126)-induced neurotoxicity via the PPARγ-autophagy pathway in neuronal cells

Prion diseases, which involve the alteration of cellular prion protein into a misfolded isoform, disrupt the central nervous systems of humans and animals alike. Prior research has suggested that peroxisome proliferator-activator receptor (PPAR)γ and autophagy provide some protection against neurode...

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Detalles Bibliográficos
Autores principales: Moon, Ji-Hong, Hong, Jeong-Min, Park, Sang-Youel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047904/
https://www.ncbi.nlm.nih.gov/pubmed/33846779
http://dx.doi.org/10.3892/mmr.2021.12069

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047904/
https://www.ncbi.nlm.nih.gov/pubmed/33846779
http://dx.doi.org/10.3892/mmr.2021.12069

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