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The antidiabetic drug troglitazone protects against PrP (106–126)-induced neurotoxicity via the PPARγ-autophagy pathway in neuronal cells
Prion diseases, which involve the alteration of cellular prion protein into a misfolded isoform, disrupt the central nervous systems of humans and animals alike. Prior research has suggested that peroxisome proliferator-activator receptor (PPAR)γ and autophagy provide some protection against neurode...
Autores principales: | Moon, Ji-Hong, Hong, Jeong-Min, Park, Sang-Youel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047904/ https://www.ncbi.nlm.nih.gov/pubmed/33846779 http://dx.doi.org/10.3892/mmr.2021.12069 |
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